# A rare case of eosinophilic jejunitis: diagnosis and management strategies

**Authors:** T Y Aaboudech, F Zouaidia, K Znati, Z Bernoussi, A Jahid

PMC · DOI: 10.1093/jscr/rjae157 · Journal of Surgical Case Reports · 2024-03-17

## TL;DR

A rare case of eosinophilic jejunitis is described, highlighting its diagnosis and successful surgical management in a young patient.

## Contribution

The paper presents a new clinical case of localized eosinophilic jejunitis without peripheral eosinophilia.

## Key findings

- The patient exhibited obstructive symptoms and jejunal stenosis with eosinophilic infiltration confirmed via surgery.
- Histological findings showed no parasitic or granulomatous lesions, confirming a localized condition.
- The patient recovered quickly post-surgery, with biopsies from other areas yielding negative results.

## Abstract

Eosinophilic gastroenteritis is a rare disease with an unknown cause, which can manifest independently or as part of a hyper-eosinophilic syndrome. The severity of the condition depends on the extent of eosinophilic infiltration and damage to the digestive tract. Diagnosis relies on histological examination, which reveals a significant presence of eosinophilic polymorphonuclear leukocytes in the digestive wall. The authors present a new case of eosinophilic gastroenteritis in a 28-year-old patient who exhibited obstructive symptoms but lacked peripheral eosinophilia. Esophagogastroduodenoscopy showed no abnormalities, but barium transit imaging revealed gastro-duodeno-jejunal dilation upstream of a tight jejunal stenosis. Surgical examination of the affected area confirmed a diffuse and transparietal eosinophilic infiltrate, with no evidence of parasitic or granulomatous lesions. Fortunately, the patient had a swift recovery following surgery. Biopsies conducted at other locations, including the gastric, hepatic, and medullary levels, produced negative results, indicating the localized nature of the condition.

## Linked entities

- **Diseases:** eosinophilic gastroenteritis (MONDO:0016129), hyper-eosinophilic syndrome (MONDO:0015691)

## Full-text entities

- **Diseases:** Eosinophilic gastroenteritis (MESH:C535952), eosinophilic jejunitis (MESH:D007579), peripheral eosinophilia (MESH:D004802), granulomatous lesions (MESH:D006105), hyper-eosinophilic syndrome (MESH:D017681)
- **Chemicals:** barium (MESH:D001464)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10948736/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC10948736/full.md

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Source: https://tomesphere.com/paper/PMC10948736