# Scrotal Dermatofibrosarcoma Protuberans in a Patient with Schizophrenia: A Case Report and Review of the Literature

**Authors:** Leah Ashton, Gabrielle R Yankelevich, Kyler W Perry, Robert L Grubb

PMC · DOI: 10.7759/cureus.54369 · Cureus · 2024-02-17

## TL;DR

A rare case of scrotal dermatofibrosarcoma protuberans in a man with schizophrenia is reported, highlighting challenges in diagnosis and treatment.

## Contribution

This is the fourth documented case of scrotal DFSP, emphasizing its rarity and management complexities in patients with schizophrenia.

## Key findings

- The patient had scrotal DFSP confirmed by wide surgical excision and radical orchiectomy.
- The case highlights challenges due to concurrent aortic dissection and schizophrenia.
- Social determinants of health delayed care and impacted treatment compliance.

## Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare spindle cell soft tissue sarcoma of the dermis and subcutaneous tissue. We present the fourth case of scrotal DFSP in the literature, identified in a 32-year-old male with schizophrenia. Wide surgical excision and radical orchiectomy were performed revealing an uninvolved testicle and DFSP of the scrotum. A unique challenge to this case was concurrent aortic dissection and schizophrenia. Social determinants of health are associated with delay in presentation and poor appointment compliance in patients with schizophrenia. Ultimately, DFSP of the scrotum is an extremely rare condition with this presentation being only the fourth report in the literature. It is important to document these unique cases to establish differential diagnoses and optimize management.

## Linked entities

- **Diseases:** schizophrenia (MONDO:0005090), dermatofibrosarcoma protuberans (MONDO:0011934)

## Full-text entities

- **Diseases:** Schizophrenia (MESH:D012559), cell soft tissue sarcoma (MESH:D018227), aortic dissection (MESH:D000784), DFSP (MESH:D018223)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10945469/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC10945469/full.md

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Source: https://tomesphere.com/paper/PMC10945469