# Gossypium hirsutum gene of unknown function Gohir.A02G161000 encodes a potential transmembrane Root UVB Sensitive 4 Protein with a putative protein-protein interaction interface

## TL;DR

This paper identifies a cotton gene with a predicted role in UVB sensitivity and plant development based on bioinformatics analysis.

## Contribution

The study reveals a new potential dimerization surface in a RUS4 protein from cotton.

## Key findings

- Gohir.A02G161000.1 encodes a plastid-localized transmembrane RUS4 protein.
- The protein has a predicted dimerization interface and is involved in auxin transport and pollen maturation.
- Sequence conservation supports functional relevance in plant UVB sensitivity.

## Abstract

A gene of unknown function, Gohir.A02G161000.1, identified in
Gossypium hirsutum
was studied using computational sequence and structure bioinformatics tools. The associated protein GhRUS4-A0A1U8JPV7 (UniProt A0A1U8JPV7) is predicted to be a plastid-localized, transmembrane root UVB-sensitive 4 (RUS4) protein with a newly identified potential dimerization surface. Evidence from homology and sequence conservation suggest involvement in auxin transport and pollen maturation.