# Synthesis of novel organophosphorus compounds via reaction of substituted 2-oxoindoline-3-ylidene with acetylenic diesters and triphenylphosphine or triphenyl phosphite

**Authors:** Mahsa Najafi, Ghasem Marandi

PMC · DOI: 10.1038/s41598-024-56774-z · 2024-03-15

## TL;DR

This paper describes a new method to create stable organophosphorus compounds using specific chemical reactions.

## Contribution

The paper introduces a novel synthetic route for functionalized 2-oxoindoline-3-ylidene compounds with phosphorus.

## Key findings

- The reaction produces stable phosphorus ylides or phosphonate esters with good yields.
- Substituted 2-oxoindoline-3-ylidene derivatives react efficiently with acetylenic esters.
- Triphenylphosphine or triphenyl phosphite are effective reagents in the synthesis.

## Abstract

An efficient reaction between triphenylphosphine or triphenyl phosphite and 2-oxoindoline-3-ylidene derivatives in the presence of acetylenic esters leads to functionalized 2-oxoindoline-3-ylidene containing phosphorus ylieds or phosphonate esters. All compounds obtained in these reactions are stable and have good yields.

## Linked entities

- **Chemicals:** triphenylphosphine (PubChem CID 11776), triphenyl phosphite (PubChem CID 7540)

## Full-text entities

- **Chemicals:** 2-oxoindoline-3-ylidene (-), triphenyl phosphite (MESH:C013318), triphenylphosphine (MESH:C061896)

## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10943016/full.md

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Source: https://tomesphere.com/paper/PMC10943016