# Primary Squamous Cell Carcinoma of the Stomach: A Case Report

**Authors:** Ygor R Fernandes, Ketlin B Morais, Ana Carolina Campos, Rodrigo S Machado

PMC · DOI: 10.7759/cureus.54188 · 2024-02-14

## TL;DR

This case report describes a rare instance of stomach cancer in a young adult, highlighting the challenges in diagnosing and understanding this unusual condition.

## Contribution

The report adds to the limited literature on gastric squamous cell carcinoma, emphasizing its diagnostic and clinical complexities.

## Key findings

- Gastric squamous cell carcinoma is extremely rare, especially in young adults.
- Immunohistochemistry is essential for accurate diagnosis due to the lack of clear risk factors.
- Multidisciplinary collaboration is crucial for managing this enigmatic cancer type.

## Abstract

Gastric squamous cell carcinoma (SCC) is a rare and puzzling entity that challenges conventional paradigms of gastric malignancies, especially in young adults. This case report presents a 22-year-old male with invasive SCC of the stomach, emphasizing the rarity of such occurrences and their diagnostic challenges. The literature review underscores the scarcity of information on gastric SCC, necessitating a critical examination of its clinical implications, etiological factors, and optimal management. The patient’s complex medical history, diagnostic journey, and treatment course are detailed, highlighting the importance of multidisciplinary collaboration and advanced diagnostic techniques. Immunohistochemistry is a crucial tool for precise tumor characterization, and the absence of established risk factors emphasizes the enigmatic nature of gastric SCC. This case report contributes to the understanding of gastric SCC, prompting further research into its unique features, etiology, and therapeutic strategies in the context of gastric cancer.

## Linked entities

- **Diseases:** gastric squamous cell carcinoma (MONDO:0006230), gastric cancer (MONDO:0001056)

## Full-text entities

- **Diseases:** Gastric squamous cell carcinoma (MESH:D002294), tumor (MESH:D009369), gastric cancer (MESH:D013274)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10941998/full.md

---
Source: https://tomesphere.com/paper/PMC10941998