# Three cases of non-infectious necrotizing stromal keratitis after corneal refractive surgery

## TL;DR

Three young women developed non-infectious corneal inflammation after eye surgery, highlighting the need for thorough pre-surgery medical history checks.

## Contribution

Highlights the importance of medical history and potential risk factors for post-surgery corneal inflammation.

## Key findings

- Three cases of non-infectious corneal inflammation occurred after refractive eye surgeries.
- Two patients had aseptic necrotizing inflammation, and one had delayed necrotizing inflammation.
- Emphasizes the need to consider vaccination and travel history pre-surgery.

## Abstract

We reported three cases of aseptic necrotizing stromal keratinitis after corneal refractive surgery (two with small incision lenticule extraction and one with femtosecond laser-laser-assisted insitu keratomileusis). There were three young women who had undergone corneal refractive surgery had white aseptic infiltrating foci along or away from the stroma in both eyes or one eye on regular review, all of whom denied systemic disease or chronic ocular disease. Two patients were diagnosed with aseptic necrotizing corneal stromal inflammation, and one patient was diagnosed with delayed necrotizing corneal stromal inflammation. In our opinion, before corneal refractive surgery, medical history inquiry is very important. More attention should be paid to patients with vaccination history and foreign travel history. In addition, the possibility of delayed corneal stromal inflammation should be considered for patients with poor binocular corrected vision.