First person – Abigail Ama Koomson and Patrice Delaney

TL;DR

This paper discusses the long-term effects of inorganic arsenic exposure during development on zebrafish liver gene expression and mating success.

Contribution

The study reveals sustained impacts of early arsenic exposure on hepatic gene expression and reproductive outcomes in zebrafish.

Findings

Developmental arsenic exposure alters hepatic gsto2 expression in zebrafish.

Exposure to inorganic arsenic reduces mating success in zebrafish.

Effects of arsenic exposure persist into adulthood in zebrafish.

Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Abigail Ama Koomson and Patrice Delaney are co-first authors on ‘
Sustained effects of developmental exposure to inorganic arsenic on hepatic gsto2 expression and mating success in zebrafish’, published in BiO. Abigail and Patrice conducted the research described in this article while Capstone student (Abigail) and PhD candidate (Patrice) in Dr Kirsten Sadler Edepli's lab at New York University Abu Dhabi. Abigail is now a PhD Student at Yale School of Medicine, New Haven, investigating the mechanisms underlying liver disease. Patrice is a Postdoctoral Research Fellow in the lab of Dr Wolfram Goessling at Harvard Medical School, Boston, focused on how aberrant exposure to anthropogenic contaminants, such as bisphenol A, interfere with hormone-regulated events in liver development.

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