# Peritoneal Recurrence of Squamous Cell Carcinoma in a Young Woman After Conization for Microinvasive Cervical Cancer

## TL;DR

A young woman developed peritoneal cancer recurrence 47 months after cervical cancer treatment with conization, suggesting a rare metastatic pathway.

## Contribution

This case report highlights a rare peritoneal recurrence of cervical cancer after conization, providing insight into possible metastatic routes.

## Key findings

- A 31-year-old woman had a peritoneal recurrence of squamous cell carcinoma 47 months after conization for microinvasive cervical cancer.
- The tumor was diagnosed as a metastasis of cervical carcinoma, likely spreading via the endometrial cavity and fallopian tube.
- Salvage chemoradiation led to a disease-free status 90 months after treatment.

## Abstract

Microinvasive squamous cell carcinoma of the cervix develops mainly in young women. As metastases rarely occur, cervical conization to preserve fertility is often performed. We report a case of peritoneal recurrence developed after conization. A 31-year-old nulligravid woman with microinvasive squamous cell carcinoma of the cervix was treated with laser conization. Pathology showed a stromal invasion of <1 mm and a longitudinal spread of 3 mm without lymphovascular space involvement. Forty-seven months after conization, a pelvic examination revealed a firm, immobile mass on the right side of the pelvis. Transvaginal ultrasonography and magnetic resonance imaging showed a 3.8-cm solid mass located right of the rectum and anterior to the sacrum. A fine-needle biopsy showed squamous cell carcinoma. The tumor was diagnosed as a metastasis of cervical carcinoma. After salvage concurrent chemoradiation, the patient was well and had no evidence of disease at 90 months after the treatment. In this case, tumor cells appear to spread through the endometrial cavity and the lumen of the fallopian tube.