# Changes in the Visual Field Test after Descemet Stripping Automated Endothelial Keratoplasty in Advanced Glaucoma

**Authors:** Noriko Toyokawa, Kaoru Araki-Sasaki, Hideya Kimura, Shinichiro Kuroda

PMC · DOI: 10.3390/jcm13051431 · Journal of Clinical Medicine · 2024-03-01

## TL;DR

This study shows that Descemet stripping automated endothelial keratoplasty can improve visual field and acuity in advanced glaucoma patients.

## Contribution

Demonstrates subjective visual field improvement after DSAEK in advanced glaucoma cases with prior trabeculectomy.

## Key findings

- 63.2% of eyes showed visual field improvement after DSAEK using HFA and/or GP testing.
- 94.7% of eyes improved by more than two lines in best-corrected visual acuity.
- No significant changes in intraocular pressure or glaucoma medication use post-surgery.

## Abstract

Background: To evaluate changes in the visual field (VF) after Descemet stripping automated endothelial keratoplasty (DSAEK) in eyes with advanced glaucoma and previous trabeculectomy. Methods: Changes in VF, best-corrected visual acuity (BCVA), intraocular pressure (IOP), and number of glaucoma medications were analyzed before and after DSAEK in 19 eyes. The VFs were evaluated using the 10-2 program of the Humphrey Field Analyzer (HFA) and/or Goldmann perimetry (GP). Results: In nine eyes, the MD improved from −22.24 ± 6.5 dB to −18.36 ± 5.1 dB in HFA. In five out of nine eyes, postoperative MD improved >1 dB compared to preoperative MD. In GP testing, 10 out of 15 eyes showed an improvement, that is, greater than 20° in VF enlargement by the isopter of I-4e and/or new detection of a smaller or darker isopter. Overall, improvement in VF with the HFA and/or GP test was observed in 12/19 (63.2%) eyes after DSAEK. Postoperative BCVA improved by more than two lines in logMAR VA in 18 of 19 (94.7%) eyes. There were no significant differences between the preoperative and postoperative IOP and the number of glaucoma medications. Conclusions: DSAEK may produce subjective improvement in the visual field as well as improved visual acuity, even in advanced glaucomatous eyes.

## Linked entities

- **Diseases:** glaucoma (MONDO:0005041)

## Full-text entities

- **Diseases:** Glaucoma (MESH:D005901), glaucomatous eyes (MESH:D005134)

## Full text

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## Figures

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## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC10934157/full.md

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Source: https://tomesphere.com/paper/PMC10934157