# Plasmablastic Myeloma: An Unusual Cause of Peripheral Facial Paralysis

**Authors:** João Dias, Irene Pinto, Catarina Vasconcelos, Vilma Marques

PMC · DOI: 10.7759/cureus.53998 · Cureus · 2024-02-11

## TL;DR

A 60-year-old man initially diagnosed with Bell's palsy was later found to have plasmablastic myeloma, highlighting the importance of monitoring and re-evaluating diagnoses.

## Contribution

The paper presents a rare case where plasmablastic myeloma was misdiagnosed as Bell's palsy, emphasizing the need for thorough clinical follow-up.

## Key findings

- Initial diagnosis of Bell's palsy was revised to plasmablastic myeloma based on clinical evolution.
- Physical Medicine and Rehabilitation specialists played a key role in identifying the correct diagnosis.
- New clinical findings and tests led to a change in therapeutic approach.

## Abstract

Peripheral facial paralysis refers to the involvement of the facial nerve (VII cranial nerve) at any point along its path, which starts from its nucleus, located in the pons, and extends to its most distal branches. The etiology is heterogeneous, including viral infections, bacterial infections, trauma, and neoplasms, among others. However, in the majority of cases, the cause is idiopathic, commonly referred to as Bell's palsy. The diagnosis is therefore one of exclusion, based in particular on the physical examination. Naturally, the diagnosis is decisive in directing the therapeutic approach. However, the signs/symptoms of the various primary pathological processes can appear late in the course of the disease. This is why the Physical Medicine and Rehabilitation specialist is particularly important, since, in addition to the initial assessment, he or she monitors the patient more closely and over a longer period of time, together with the team of therapists. New clinical findings and diagnostic tests requested accordingly can dramatically change the initial diagnosis and guide new treatments. We present the clinical case of a 60-year-old man initially diagnosed with Bell's palsy, whose poor clinical evolution and new clinical findings during the rehabilitation program led to the diagnosis of plasmablastic myeloma and a radically different therapeutic approach.

## Linked entities

- **Diseases:** Bell's palsy (MONDO:0005665)

## Full-text entities

- **Diseases:** neoplasms (MESH:D009369), Bell's palsy (MESH:D020330), viral infections (MESH:D014777), Facial Paralysis (MESH:D005158), bacterial infections (MESH:D001424), Plasmablastic Myeloma (MESH:D000069293), trauma (MESH:D014947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10928803/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC10928803/full.md

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Source: https://tomesphere.com/paper/PMC10928803