# Capgras Syndrome, Multiple Sclerosis, and COVID-19 Infection: A Case Report

## TL;DR

A 68-year-old woman with multiple sclerosis developed Capgras syndrome after a COVID-19 infection and was successfully treated with quetiapine.

## Contribution

This case report highlights a rare association between Capgras syndrome, multiple sclerosis, and post-COVID-19 illness.

## Key findings

- Capgras syndrome occurred in a patient with multiple sclerosis following a COVID-19 infection.
- Quetiapine treatment led to full resolution of Capgras syndrome symptoms.
- The case suggests a possible link between neurological conditions and post-viral psychiatric symptoms.

## Abstract

Capgras syndrome is a psychotic illness characterized by an unshaken false belief in having a close family member replaced by an imposter when there is no evidence of such. The patient described in this case report is a 68-year-old Caucasian female who presented with Capgras syndrome in the context of chronic progressive multiple sclerosis (MS) following an acute COVID-19 illness. She was treated with quetiapine with full resolution of symptoms.