# Lymph Node Penetration From Gastric Burkitt Lymphoma in a Patient Living With HIV/AIDS

**Authors:** Ricardo José Razera, Ronaldo Modesto de Souza-Filho, Rosely Antunes Patzina, Jose C Ardengh, Richard Calanca

PMC · DOI: 10.7759/cureus.53905 · Cureus · 2024-02-09

## TL;DR

This case report highlights a rare instance of gastric Burkitt lymphoma in an HIV/AIDS patient, emphasizing the importance of considering this diagnosis even in patients with adequate immunity.

## Contribution

The novelty lies in presenting a rare case of metastatic gastric Burkitt lymphoma in an HIV/AIDS patient with adequate immunity, underscoring the need for vigilance in diagnosis.

## Key findings

- Burkitt lymphoma can occur in HIV/AIDS patients with high CD4+ T lymphocyte counts.
- A 32-year-old HIV/AIDS patient presented with metastatic gastric Burkitt lymphoma despite adequate immunity.
- The case underscores the importance of thorough history and physical examination in diagnosing rare lymphomas.

## Abstract

Non-Hodgkin's Lymphoma (NHL) in people living with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) still constitutes a reality of high morbidity and mortality, sometimes not respecting the patient's degree of immunosuppression as it can even occur in those with a high CD4+ T lymphocyte count. Burkitt's lymphoma, in this sense, has been shown to be one of the main subtypes of this condition in this group of patients. This case report concerns a 32-year-old man diagnosed with metastatic gastric Burkitt's lymphoma after one month of his admission to a tertiary hospital for neurological complaints. The aim of this study is to raise an alert to suspect this diagnosis even in patients with adequate immunity, a well-done history, and a physical examination, which are the main pillars for reaching a diagnosis.

## Linked entities

- **Diseases:** Non-Hodgkin's Lymphoma (MONDO:0018908), Burkitt's lymphoma (MONDO:0007243)

## Full-text entities

- **Genes:** CD4 (CD4 molecule) [NCBI Gene 920] {aka CD4mut, IMD79, Leu-3, OKT4D, T4}
- **Diseases:** neurological (MESH:D009461), Lymph Node (MESH:D000072717), Human Immunodeficiency Virus (MESH:D015658), NHL (MESH:D008228), Burkitt Lymphoma (MESH:D002051), Acquired Immunodeficiency Syndrome (MESH:D000163)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10924991/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC10924991/full.md

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Source: https://tomesphere.com/paper/PMC10924991