# Does Asthma Increase the Odds of Suicidal Thoughts, Plans, and Attempts?

**Authors:** Karan Varshney, Pavan Shet, Brandon George, Matthew Wintersteen

PMC · DOI: 10.7759/cureus.53865 · Cureus · 2024-02-08

## TL;DR

This study finds that asthma is initially linked to higher odds of suicidal thoughts and attempts, but this link disappears after accounting for other factors.

## Contribution

The novel contribution is using propensity score matching to assess the relationship between asthma and suicidality while controlling for confounders.

## Key findings

- Before matching, asthmatics had 31.2% higher odds of suicidal thoughts and 97.4% higher odds of suicide attempts.
- After controlling for confounders, no significant association remained between asthma and suicidality measures.

## Abstract

Background

Asthma is a chronic inflammatory disease of the airways affecting more than 250 million people worldwide. In the past, a possible relationship between asthma and suicidality has been hypothesized. However, further research is required as this link has not been clearly established. Our objective was to use propensity score matching to answer the following research question: does having asthma increase one’s odds of developing suicidality throughout their lifetime and, if so, how large is this increase?

Methodology

We utilized data from the 2018 National Survey on Drug Use and Health. We analyzed the relationship between currently having asthma and having had suicidal thoughts, suicide plans, and suicide attempts over the past 12 months. Chi-square analyses were performed both before and after completing propensity score matching.

Results

Before matching, it was found that, compared to individuals without asthma, asthmatic individuals had 31.2% higher odds of having suicidal thoughts (p = 0.010) and 97.4% higher odds of a suicide attempt (p = 0.012). After controlling for confounders by matching, there was no longer a relationship between having asthma and suicidal thoughts (p = 0.707), suicidal plans (p = 0.523), and suicidal attempts (p = 0.260).

Conclusions

These findings highlight that while asthma may appear to be associated with suicidality, this association does not persist after controlling for confounding factors. Hence, it is recommended that more research be conducted on this topic and that possible confounders be further researched. In particular, there is a need to better understand the role of social determinants and other contributors to health outcomes.

## Linked entities

- **Diseases:** asthma (MONDO:0004979)

## Full-text entities

- **Diseases:** inflammatory disease of the airways (MESH:D007249), Asthma (MESH:D001249), asthmatic (MESH:D013224)

## Full text

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC10924673/full.md

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Source: https://tomesphere.com/paper/PMC10924673