# Remitting Seronegative Symmetrical Synovitis With Pitting Edema in an Adolescent

## TL;DR

This paper reports a rare case of a joint inflammation condition in an adolescent, typically seen in older adults.

## Contribution

The novelty is the presentation of the first reported case of RS3PE in a pediatric patient.

## Key findings

- RS3PE was diagnosed in a pediatric patient, a rare occurrence.
- The condition showed typical features like symmetrical joint inflammation and pitting edema.
- The patient responded well to low-dose steroids, consistent with RS3PE characteristics.

## Abstract

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare clinical entity characterized by symmetrical tenosynovitis of both hands and ankles with pitting edema, negative rheumatoid factor (RF), absence of radiographic erosions, and excellent response to low-dose steroids. It is classically associated with elderly patients but may occur in younger patients, with only one case reported in the pediatric age. We report a case of RS3PE diagnosed in a pediatric patient.