# Dandy-Walker Malformation with Neonatal Meningitis: A Case Report

**Authors:** Bishal Pradhan, Bishal Sharma, Pratistha Acharya, Suraksha Thapa, Jyoti Chand, Simran Bista

PMC · DOI: 10.31729/jnma.8472 · JNMA: Journal of the Nepal Medical Association · 2024-02-29

## TL;DR

This case report describes a neonate diagnosed with Dandy-Walker variant and meningitis, highlighting the importance of postnatal brain imaging for accurate diagnosis.

## Contribution

The novelty lies in presenting a rare case of Dandy-Walker variant diagnosed postnatally alongside neonatal meningitis.

## Key findings

- Dandy-Walker variant was diagnosed postnatally using brain MRI in a neonate with meningitis.
- Symptoms included petechiae and cyanosis at birth, with prenatal diagnosis potentially missed.
- MRI is emphasized as the most effective diagnostic tool for Dandy-Walker syndrome after birth.

## Abstract

Dandy-Walker syndrome is a rare congenital central nervous system malformation. Dandy-Walker variant is characterised by cerebellar vermian hypoplasia, cystic fourth ventricular dilatation, and normal posterior fossa volume. Various prenatal tests such as ultrasound, fetal magnetic resonance imaging, and amniocentesis can help diagnose Dandy-Walker syndrome. Here, we report a case of the Dandy-Walker variant with meningitis in a neonate admitted to the neonatal intensive care unit due to multiple petechiae on the anterior abdominal wall, accompanied by peripheral cyanosis at the time of birth. Although maximum cases are diagnosed prenatally, some cases might be missed due to inadequate antenatal examination. Magnetic imaging resonance of the brain is best for the diagnosis of Dandy-Walker syndrome postnatally.

## Linked entities

- **Diseases:** Dandy-Walker syndrome (MONDO:0009072), meningitis (MONDO:0021108)

## Full-text entities

- **Diseases:** Neonatal Meningitis (MESH:D007232), cystic fourth ventricular dilatation (MESH:D018297), Dandy-Walker (MESH:D003616), central nervous system malformation (MESH:D020785), cyanosis (MESH:D003490), petechiae (MESH:D011693), cerebellar vermian hypoplasia (MESH:C562568), meningitis (MESH:D008580)

## Full text

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## Figures

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC10924517/full.md

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Source: https://tomesphere.com/paper/PMC10924517