# Turning back time: effects of young plasma on pan epigenetic clocks and implications for the heart

**Authors:** Kathleen C. Woulfe, Emma L. Robinson

PMC · DOI: 10.20517/jca.2023.44 · 2024-03-07

## Full-text entities

- **Genes:** Nppb (natriuretic peptide B) [NCBI Gene 25105] {aka BNP, Bnf}, Il6 (interleukin 6) [NCBI Gene 24498] {aka ILg6, Ifnb2}, TET2 (tet methylcytosine dioxygenase 2) [NCBI Gene 54790] {aka IMD75, KIAA1546, MDS}, Nppa (natriuretic peptide A) [NCBI Gene 24602] {aka ANF, ANP, CDD, Pnd, RATANF}, Nppb (natriuretic peptide type B) [NCBI Gene 18158] {aka BNF, BNP, Iso-ANP}, Tnf (tumor necrosis factor) [NCBI Gene 24835] {aka RATTNF, TNF-alpha, Tnfa}
- **Diseases:** frailty (MESH:D000073496), mitochondrial dysfunction (MESH:D028361), cardiotoxic (MESH:D066126), cardiovascular and cerebrovascular diseases (MESH:D002318), cardiac hypertrophy (MESH:D006332), dysbiosis (MESH:D064806), chronic inflammation (MESH:D007249), cardiac fibrosis (MESH:D005355), heart failure (MESH:D006333), cardiac remodeling (MESH:D020257), aging-associated diseases (MESH:C564653), cardiac dysfunction (MESH:D006331), function (MESH:D003291), cancers (MESH:D009369), endothelial cell dysfunction (MESH:D055954), degenerative diseases (MESH:D019636), atherosclerosis (MESH:D050197)
- **Chemicals:** acetylcholine (MESH:D000109)
- **Species:** Sus scrofa (pig, species) [taxon 9823], Homo sapiens (human, species) [taxon 9606], Rattus norvegicus (brown rat, species) [taxon 10116], Mus musculus (house mouse, species) [taxon 10090]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10919904/full.md

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Source: https://tomesphere.com/paper/PMC10919904