Intravascular Large B-cell Lymphoma Presenting with Lung Adenocarcinoma: A Case Report and Literature Review
Tongtong WANG, Xiaoyue CHEN, Guochen DUAN, Xiaopeng ZHANG, Qingtao ZHAO, Shun XU, Huanfen ZHAO

TL;DR
This paper reports a rare case of lung adenocarcinoma combined with intravascular large B-cell lymphoma and reviews clinical features to improve diagnosis.
Contribution
The novelty lies in presenting a rare coexistence of lung adenocarcinoma and IVLBCL, emphasizing the importance of accurate diagnosis.
Findings
A case of lung adenocarcinoma combined with IVLBCL was identified through biopsy and surgery.
Clinical and pathological features were analyzed to enhance recognition of this rare condition.
Literature review highlights the importance of considering IVLBCL in differential diagnoses of lung tumors.
Abstract
血管内大B细胞淋巴瘤(intravascular large B-cell lymphoma, IVLBCL)是一种侵袭性结外大B细胞淋巴瘤,在同一器官与其他恶性肿瘤同时发生非常罕见,尤其是肺。本文报道1例肺腺癌合并IVLBCL的罕见病例。患者因腹泻伴发热、咳嗽入院。胸部计算机断层扫描(computed tomography, CT)示右肺上叶不规则斑片状高密度影,边缘有磨玻璃影。入院后给予患者抗感染等治疗,但仍有间断低热(最高37.5 oC)。经皮肺穿刺活检(percutaneous lung biopsy, PLB)病理诊断为贴壁生长为主的腺癌,局部考虑浸润。手术后病理诊断为肺浸润性非黏液性腺癌合并IVLBCL。本文通过分析其临床病理特征,并复习相关文献,以提高临床和病理医师对该肿瘤的认识,避免漏诊或误诊。 Clinical characteristics of 58 cases pulmonary IVLBCL
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Taxonomy
TopicsSports and Physical Education Research · Child Development and Education
