# Anorexia Nervosa With Intermittent Fever Due to Diet-Induced Thermogenesis: A Case Report

**Authors:** Atsuhiro Ijiri, Soichiro Seno, Nobuaki Kiriu, Hiroshi Kato, Tetsuro Kiyozumi

PMC · DOI: 10.7759/cureus.53647 · 2024-02-05

## TL;DR

A woman with anorexia nervosa developed intermittent fever due to high protein intake during tube feeding, not from infection.

## Contribution

Identifies diet-induced thermogenesis as a cause of fever in anorexia nervosa patients undergoing tube feeding.

## Key findings

- Intermittent fever was linked to high protein intake during tube feeding.
- No infection or drug-related causes were found for the fever.
- Diet-induced thermogenesis should be considered in similar clinical cases.

## Abstract

Diet-induced thermogenesis, influenced primarily by protein intake, generates energy from food. Herein, we present the case of anorexia nervosa in a 30-year-old woman, who developed intermittent fever while transitioning from continuous to intermittent tube feeding, with an increase in protein intake. Extensive investigations ruled out infection- or drug-related causes, indicating that intermittent fever resulted from diet-induced thermogenesis due to high protein administration. Recognizing the potential for diet-induced thermogenesis in cases of fever during tube feeding is crucial to avoid unnecessary antibiotic use and prevent the discontinuation of essential medications.

## Linked entities

- **Diseases:** anorexia nervosa (MONDO:0005351)

## Full-text entities

- **Diseases:** Fever (MESH:D005334), Anorexia Nervosa (MESH:D000856), infection (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10917452/full.md

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Source: https://tomesphere.com/paper/PMC10917452