# Recurrent Thyrotoxic Periodic Paralysis As the Sole Clinical Manifestation of Untreated Hyperthyroidism

**Authors:** Zhanna Zavgorodneva, Muzammil Khan

PMC · DOI: 10.7759/cureus.53581 · Cureus · 2024-02-04

## TL;DR

A 32-year-old African American patient presented with thyrotoxic periodic paralysis as the sole sign of untreated hyperthyroidism.

## Contribution

This case highlights TPP as a primary manifestation of hyperthyroidism in an atypical demographic.

## Key findings

- TPP was the sole clinical manifestation of untreated hyperthyroidism in an African American patient.
- Symptoms resolved after correcting electrolyte abnormalities.

## Abstract

Thyrotoxic periodic paralysis (TPP) is a complication of hyperthyroidism that predominantly affects the Asian population. Episodes of muscle paralysis typically coincide with symptoms of hyperthyroidism. However, we present a unique case of TPP in a 32-year-old African American patient where TPP served as the primary manifestation of thyrotoxicosis. The patient was discharged with a resolution of symptoms after correcting electrolyte abnormalities.

## Linked entities

- **Diseases:** hyperthyroidism (MONDO:0004425), thyrotoxic periodic paralysis (MONDO:0019201)

## Full-text entities

- **Diseases:** TPP (OMIM:188580), muscle paralysis (MESH:D012133), electrolyte abnormalities (MESH:D014883), Hyperthyroidism (MESH:D006980), thyrotoxicosis (MESH:C566386)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10914640/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC10914640/full.md

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Source: https://tomesphere.com/paper/PMC10914640