# A Triggering Event of Central Retinal Artery Occlusion With Concurrent Ischemic Stroke

**Authors:** Lai Zhong Yang, Qi Zhe Ngoo, Vithiaa Nilamani, Rafidah Sudarno

PMC · DOI: 10.7759/cureus.53577 · Cureus · 2024-02-04

## TL;DR

A young man experienced sudden vision loss and stroke, revealing a rare condition involving the eye and brain.

## Contribution

This case highlights a rare occurrence of central retinal artery occlusion and ischemic stroke in a young patient.

## Key findings

- The patient showed signs of central retinal artery occlusion with a cherry red spot and optic nerve dysfunction.
- He developed acute ischemic stroke while in the hospital, with no evidence of atrial fibrillation or other major artery thrombosis.
- Treatment with aspirin and atorvastatin led to slight improvement in vision.

## Abstract

We report a case of central retinal artery occlusion with concurrent ischemic stroke in a young patient. A 34-year-old Malay gentleman, an ex-smoker with underlying dyslipidemia, however, not on medication or follow-up, presented with acute, generalized, and painless right eye blurring of vision for one day. He also complained of on-and-off headaches for the past three months prior to the presentation. Visual acuity assessment demonstrated hand movement in the right eye, whereas in the left eye, it was 6/6, along with a right eye relative afferent pupillary defect. His right eye showed reduced optic nerve function and unremarkable anterior segment, with fundus examination revealing the presence of a cherry red spot, pale macula, boxcarring pattern over superior arcuate, and vascularized retina over inferior optic disc with blurred optic disc margin. The left eye examination was unremarkable. All cranial nerves were intact, except for the optic nerve. He was admitted to the ward. While in the ward, he developed a sudden onset of left-sided upper and lower limb weakness and numbness and was diagnosed with acute ischemic stroke. Blood investigations showed raised low-density lipoprotein cholesterol of 3.51 mmol/L, anti-nuclear antibody (ANA) positive, with electrocardiogram (ECG) sinus rhythm, and no atrial fibrillation. The echocardiogram was normal, and computed tomography angiography of the brain showed non-opacification at the origin and proximal part of the right ophthalmic artery, suspicious of thrombosis with distal reconstitution, with no evidence of thrombosis in the rest of neck and intracranial arteries. The patient was started on aspirin 150 mg once a day and atorvastatin 20 mg at night; subsequently, his vision improved slightly.

## Linked entities

- **Chemicals:** aspirin (PubChem CID 2244), atorvastatin (PubChem CID 60823)
- **Diseases:** central retinal artery occlusion (MONDO:0001633), ischemic stroke (MONDO:1060198), dyslipidemia (MONDO:0002525)

## Full-text entities

- **Diseases:** weakness (MESH:D018908), Ischemic Stroke (MESH:D002544), atrial fibrillation (MESH:D001281), blurring of vision (MESH:D014786), Retinal Artery Occlusion (MESH:D015356), headaches (MESH:D006261), afferent pupillary defect (MESH:D011681), numbness (MESH:D006987), thrombosis (MESH:D013927), acute ischemic stroke (MESH:D000083242), dyslipidemia (MESH:D050171)
- **Chemicals:** atorvastatin (MESH:D000069059), aspirin (MESH:D001241)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC10914528/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10914528/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC10914528/full.md

---
Source: https://tomesphere.com/paper/PMC10914528