# A Man in His Forties with Recurrent Cat-Scratch Disease

**Authors:** Sara López-Rueda, Benjamin Valente-Acosta, Adrian Murillo-Zolezzi, Francisco Moreno-Sánchez, Irma Hoyo-Ulloa, Jesús Javier Baquera-Heredia

PMC · DOI: 10.1155/2024/4411133 · Case Reports in Infectious Diseases · 2024-02-27

## TL;DR

A 45-year-old man experienced a recurrence of cat-scratch disease two years after his initial infection, which was successfully treated with azithromycin.

## Contribution

This case report highlights a rare recurrence of cat-scratch disease and its successful treatment with azithromycin.

## Key findings

- A 45-year-old man with a prior history of CSD presented with groin lymphadenopathy and was diagnosed with a recurrence.
- Positive serology and histopathological findings confirmed the diagnosis of CSD.
- Azithromycin treatment led to complete resolution of symptoms.

## Abstract

Cat-scratch disease (CSD) is a self-limited zoonotic infection transmitted by felines caused by the Gram-negative bacillus Bartonella henselae. It usually presents with lymphadenopathy and constitutional symptoms that resolve within eight weeks, with, or without antibiotic treatment. The diagnosis is made by serology, molecular diagnosis in a biopsy, or a positive culture. The recurrence or reactivation of B. henselae has rarely been reported. We present the case of a 45-year-old man with a history of CSD two years before who presented to the clinic with groin lymphadenopathy. The patient had a history of close contact with felines though no known risk exposure was reported. The diagnosis was made with a positive serology suggestive of recent infection along with histopathological changes suggestive of CSD. Subsequently, azithromycin was administered with complete resolution of symptoms.

## Linked entities

- **Chemicals:** azithromycin (PubChem CID 447043)
- **Diseases:** cat-scratch disease (MONDO:0005692), lymphadenopathy (MONDO:0005833)

## Full-text entities

- **Diseases:** infection (MESH:D007239), CSD (MESH:D002372), lymphadenopathy (MESH:D008206)
- **Species:** Bartonella henselae (species) [taxon 38323], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10914428/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC10914428/full.md

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Source: https://tomesphere.com/paper/PMC10914428