# 3-Year Post-Transcatheter Aortic Valve Replacement (TAVR) Restenosis: A Rare Complication

**Authors:** Ijeoma Orabueze, Olushola Ogunleye, Mark Harrison

PMC · DOI: 10.7759/cureus.53515 · Cureus · 2024-02-03

## TL;DR

This paper reports a rare case of aortic valve restenosis three years after a TAVR procedure in a 70-year-old woman.

## Contribution

The paper highlights a rare complication of early valve degeneration following TAVR.

## Key findings

- A 70-year-old female experienced worsening shortness of breath three years after TAVR.
- She was found to have early valve degeneration, a rare complication of TAVR.
- Bioprosthetic valve failure rates were previously reported as low over five years.

## Abstract

The pathophysiology of aortic valve stenosis is degenerative and calcific. It may be exacerbated by atherosclerotic processes characterized by lipid accumulation and inflammation. When the stenosis gets hemodynamically severe, the valves would need to be replaced. They could be replaced using mechanical or bioprosthetic heart valves. Balloon-expandable (BE) transcatheter heart valves (THVs) were compared to the self-expanding (SE) THVs and it was found that the rate of bioprosthetic valve failure was low over a five-year period. We present the case of a 70-year-old female who presented with worsening shortness of breath three years after transcatheter aortic valve replacement and was found to have early valve degeneration.

## Linked entities

- **Diseases:** aortic valve stenosis (MONDO:0042981)

## Full-text entities

- **Diseases:** valve degeneration (MESH:D006349), calcific (MESH:D002114), inflammation (MESH:D007249), atherosclerotic (MESH:D050197), aortic valve stenosis (MESH:D001024), stenosis (MESH:D003251), shortness of breath (MESH:D004417)
- **Chemicals:** lipid (MESH:D008055)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10911685/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC10911685/full.md

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Source: https://tomesphere.com/paper/PMC10911685