# Retraction: Kinesin family member 3A stimulates cell proliferation, migration, and invasion of bladder cancer cells in vitro and in vivo

PMC · DOI: 10.1002/2211-5463.13756 · FEBS Open Bio · 2023-12-27

## TL;DR

This retracted study claimed that a protein called Kinesin 3A promotes bladder cancer cell growth and spread, but the findings are unreliable due to image duplication.

## Contribution

The paper was retracted due to inappropriate image duplication, invalidating its conclusions about Kinesin family member 3A's role in bladder cancer.

## Key findings

- The study was retracted due to image duplication with a prior article.
- The conclusions about Kinesin 3A's role in bladder cancer are considered compromised.
- The retraction was agreed upon by the journal editors and publisher.

## Abstract

Kinesin family member 3A stimulates cell proliferation, migration, and invasion of bladder cancer cells in vitro and in vivo. Q. Zhou, J. Yu, Q. Zheng, T. Wu, Z. Ji, Y. Zhuo. FEBS Open Bio 11, 1487–1496.

https://doi.org/10.1002/2211-5463.12768.

The above article, published online on November 27, 2019, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the Editor‐in‐Chief Miguel A. De la Rosa, FEBS Press, and John Wiley and Sons Ltd. The retraction has been agreed following an investigation into concerns raised by a third party, which revealed inappropriate image duplications between this article and a previously published article [1]. Thus, the editors consider the conclusions of this manuscript substantially compromised.

[1] Kun Zuo, Youhong Zhao, Yukun Zheng, De Chen, Xiaoli Liu, Song Du & Qing Liu (2019) Long non‐coding RNA XIST promotes malignant behavior of epithelial ovarian cancer. OncoTargets and Therapy, 12: 7261–7267. DOI: 10.2147/OTT.S204369.

## Linked entities

- **Diseases:** bladder cancer (MONDO:0004986)

## Full-text entities

- **Genes:** KIF3A (kinesin family member 3A) [NCBI Gene 11127] {aka FLA10, KLP-20}, XIST (X inactive specific transcript) [NCBI Gene 7503] {aka DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66}
- **Diseases:** bladder cancer (MESH:D001749), epithelial ovarian cancer (MESH:D000077216)

## Full text

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Source: https://tomesphere.com/paper/PMC10909961