# Partial Segmental Thrombosis of the Corpus Cavernosum Associated With Inappropriate Sildenafil Use

**Authors:** Henry G Danchi, Carl Kay, Steven R Hole, Austin Baraki

PMC · DOI: 10.7759/cureus.53462 · Cureus · 2024-02-02

## TL;DR

A man developed partial segmental thrombosis of the corpus cavernosum after using sildenafil without a medical need, and was successfully treated with anticoagulation.

## Contribution

This case adds to the limited literature on sildenafil's association with PSTCC and its potential therapeutic use.

## Key findings

- PSTCC was diagnosed via MRI and treated successfully with anticoagulation.
- Sildenafil use is a rare inciting factor for PSTCC, with only two prior similar cases reported.
- Sildenafil has been used therapeutically in managing PSTCC in a previous case.

## Abstract

The case presented is of a 39-year-old male with severe right groin pain and perineal pain the morning after sexual intercourse with the use of sildenafil without a diagnosis of erectile dysfunction. Partial segmental thrombosis of the corpus cavernosum (PSTCC) was diagnosed using magnetic resonance imaging and treated with direct oral anticoagulation without complications. Sildenafil use has been noted as an inciting factor for PSTCC in only two other cases of less than 60 cases reported in the literature and has even been used successfully as a component of therapeutic management of PSTCC in another previous case.

## Linked entities

- **Chemicals:** sildenafil (PubChem CID 135398744)
- **Diseases:** erectile dysfunction (MONDO:0005362)

## Full-text entities

- **Diseases:** erectile dysfunction (MESH:D007172), groin pain (MESH:D010146), perineal pain (MESH:D009437), PSTCC (MESH:C537538)
- **Chemicals:** Sildenafil (MESH:D000068677)

## Full text

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## Figures

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC10909401/full.md

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Source: https://tomesphere.com/paper/PMC10909401