# Acute Pancreatitis Leading to the Diagnosis of Presymptomatic Crohn’s Disease: A Pediatric Case Report

**Authors:** Yuji Fujita, Keiichi Tominaga, Takanao Tanaka, Akira Yamamiya, Atsushi Irisawa, Kazuyuki Ishida, Takashi Ishige, Shigemi Yoshihara

PMC · DOI: 10.7759/cureus.53397 · Cureus · 2024-02-01

## TL;DR

A teenage boy with acute pancreatitis was later found to have early, asymptomatic Crohn’s disease in his small intestine.

## Contribution

This case highlights the rare possibility of Crohn’s disease being diagnosed before symptoms appear, following acute pancreatitis.

## Key findings

- The patient had Crohn’s disease in the jejunum without typical symptoms like diarrhea or blood in stool.
- Acute pancreatitis occurred before the diagnosis of inflammatory bowel disease.
- CD with only jejunal involvement (Montreal classification L4) is extremely rare and was diagnosed early.

## Abstract

A 14-year-old boy presented with fever and abdominal pain and was diagnosed with acute pancreatitis based on computed tomography findings. The patient had neither diarrhea nor bloody stool but was diagnosed with microcytic anemia. Endoscopic examination revealed a cobblestone pattern and longitudinal ulcer scars in the jejunum. However, no abnormal findings were observed in the ileum or colon. Endoscopic ultrasound-guided fine-needle aspiration was performed from pancreatic body-tail. Pathological examination revealed no evidence of autoimmune pancreatitis (AIP). It was unclear from pathological examination whether idiopathic pancreatitis had self-limitedly improved or whether it was AIP localized to the pancreatic head. The patient was diagnosed with asymptomatic small-bowel Crohn's disease (CD), which may have been two unrelated events of acute pancreatitis. Acute pancreatitis may precede a diagnosis of inflammatory bowel disease. CD with only jejunal involvement (Montreal classification L4) is extremely rare, and we were able to diagnose it early.

## Linked entities

- **Diseases:** acute pancreatitis (MONDO:0006515), Crohn's disease (MONDO:0005011), inflammatory bowel disease (MONDO:0005265), microcytic anemia (MONDO:0001245), autoimmune pancreatitis (MONDO:0015175)

## Full-text entities

- **Diseases:** AIP (MESH:D000081012), Acute Pancreatitis (MESH:D010195), inflammatory bowel disease (MESH:D015212), ulcer (MESH:D014456), microcytic anemia (MESH:C536357), diarrhea (MESH:D003967), abdominal pain (MESH:D015746), CD (MESH:D003424), fever (MESH:D005334)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC10908432/full.md

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10908432/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC10908432/full.md

---
Source: https://tomesphere.com/paper/PMC10908432