# Residual calcified material volume of β–tricalcium phosphate with platelet-rich fibrin in unilateral alveolar bone graft

**Authors:** Chon T. Ho Nguyen, Minh H. Bui, Phuong H. Lam

PMC · DOI: 10.1186/s40902-024-00420-1 · Maxillofacial Plastic and Reconstructive Surgery · 2024-03-01

## TL;DR

This study found that β-TCP with PRF is effective for bone grafts, with better results in younger patients under 12 years old.

## Contribution

The study compares clinical outcomes of bone grafts in two age groups using β-TCP and PRF.

## Key findings

- Younger patients (12 and under) had significantly higher residual calcified material (63.53%) six months post-surgery.
- The younger group also showed greater labiopalatal thickness (5.72 mm) compared to older patients.
- β-TCP and PRF combination showed acceptable clinical effectiveness in alveolar bone grafts.

## Abstract

This study aimed to evaluate the effectiveness of β-tricalcium phosphate (β-TCP) and platelet-rich fibrin (PRF) in unilateral alveolar bone graft, involving the percentage of residual calcified material and the average labiopalatal thickness of the grafts on cone beam computed tomography at 6 months after surgery, comparing two age groups 12 years and under and over 12 years old.

The mean preoperative defect volume was 0.93 ± 0.20 cm3, with no significant difference between the two groups (p = 0.652). In the postoperative period, we did not record any abnormal bleeding and no infection was observed. Six months after surgery, the mean percentage of residual calcified material was 63.53 ± 16.48% with a significantly higher difference in the age group 12 and under (p < 0.001), and the mean average labiopalatal thickness of the grafted bone was 5.72 ± 1.09 mm with a significantly higher difference in the age group 12 and under (p = 0.011).

Using β-TCP and PRF in alveolar bone graft surgery has acceptable effectiveness clinically and on CBCT images, with significantly higher differences of the percentage of residual calcified material and the average labiopalatal thickness of the grafted bone in the group 12 years old and younger than in the older group.

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), infection (MESH:D007239)
- **Chemicals:** beta-TCP (MESH:C485817)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC10907557/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10907557/full.md

## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC10907557/full.md

---
Source: https://tomesphere.com/paper/PMC10907557