# Investigation of acute severe hepatitis in children: A review of liver transplant data, Canada, 2021–2022

## TL;DR

This paper reviews liver transplant data in Canada to investigate a reported rise in severe hepatitis in children.

## Contribution

It provides Canadian-specific data showing no increase in liver transplants related to the hepatitis cases.

## Key findings

- No observable increase in liver transplants was noted in Canada in 2022.
- Federal, provincial, and territorial investigations confirmed no significant rise in cases.
- The data contribute to understanding the global context of the hepatitis outbreak.

## Abstract

An increase in severe acute hepatitis of unknown etiology was first reported in the United Kingdom in April 2022. Following this report, the Public Health Agency of Canada connected with three paediatric liver transplant centres across Canada to determine if an increase in liver transplants was noted. Data demonstrated no observable increase in the number of transplants conducted in 2022. These data in conjunction with a federal, provincial, territorial investigation provided insight into the situation in Canada.