# An “Awakener” Patient Suffering From Treatment-Resistant Depression Following Adjunctive Cariprazine

**Authors:** Konstantinos Bonotis

PMC · DOI: 10.7759/cureus.53246 · 2024-01-30

## TL;DR

A patient with treatment-resistant depression showed rapid improvement after adding cariprazine to their medication.

## Contribution

This case highlights the potential effectiveness of cariprazine as an adjunct in treatment-resistant depression.

## Key findings

- Adjunctive cariprazine led to immediate improvement in the patient's symptoms.
- The patient had previously failed multiple treatment attempts for depression.

## Abstract

This report presents a case of particular interest in terms of course and therapeutic outcomes, concerning a patient suffering from treatment-resistant depression in whom adjunctive cariprazine to medication brought about an immediate overall improvement in symptomatology. Informed written consent was obtained from the subject for publication of the case.

## Linked entities

- **Chemicals:** cariprazine (PubChem CID 11154555)
- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** Treatment-Resistant Depression (MESH:D061218)
- **Chemicals:** Cariprazine (MESH:C533287)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC10904079