Adrenal Gland Incidentaloma: A Rare Case of Extranodal B-cell Lymphoma

TL;DR

A rare case of B-cell lymphoma in the adrenal gland is presented, emphasizing the need for timely diagnosis and treatment.

Contribution

This paper reports a rare case of primary adrenal diffuse large B-cell lymphoma and underscores the importance of prompt diagnosis.

Findings

A 68-year-old man was diagnosed with nongerminal center-type DLBCL in the adrenal gland.

Surgical and pharmacologic treatment was necessary for managing this rare adrenal malignancy.

Abstract

The prevalence of adrenal incidentalomas (i.e., incidental findings) has grown in recent years with the evolution of imaging methods. Adrenal masses can be benign or malignant. Malignant ones are less frequent, but the detection of primary adrenal neoplasms is even less frequent, especially in the case of a diffuse large B-cell lymphoma (DLBCL). This case concerns a 68-year-old man who presented to the emergency department due to fatigue and anorexia. Given his blood test results on admission, he underwent a computed tomography (CT) with angiography that identified a mass in the left adrenal gland with displacement of the ipsilateral kidney. Left tumorectomy, adrenalectomy, and nephrectomy were performed, and the mass corresponded to a nongerminal center-type DLBCL. This case highlights the importance of prompt diagnosis and surgical and pharmacologic treatment of DLBCL.

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