# A Case Report Based on a Holistic Approach to Improve Assisted Reproductive Technology (ART) Pregnancy Outcomes in a Patient With Thyroid Dysfunction

**Authors:** Neha Nawale, Akash More, Shilpa Dutta, Namrata Choudhary, Sanket Mahajan, Shivani Khemani

PMC · DOI: 10.7759/cureus.53144 · Cureus · 2024-01-29

## TL;DR

A 34-year-old woman with hypothyroidism and infertility improved her health through a combination of levothyroxine, yoga, and meditation, leading to a successful pregnancy.

## Contribution

This case report demonstrates the potential of integrating holistic therapies with conventional treatment to improve ART outcomes in hypothyroid patients.

## Key findings

- The patient's BMI improved from 28 to 24 after six months of therapy.
- Thyroid-stimulating hormone (TSH) levels returned to the normal range.
- A successful clinical pregnancy was achieved following IVF treatment.

## Abstract

To address infertility in a 34-year-old woman with hypothyroidism, this case study investigated an integrated holistic therapy approach. The woman presented with primary infertility and sought treatment at an infertility centre in Maharashtra, India. She underwent thorough evaluations for infertility, revealing a history of hypothyroidism. The therapy strategy included a six-month course of 50 mg levothyroxine, along with yoga and yog nidra. The yoga interventions, incorporating techniques such as surya namaskar, kriyas, yoga asanas, and pranayama, proved beneficial for weight management, stress reduction, and overall well-being. The deep relaxation method known as yog nidra played a crucial role in achieving hormonal balance. After six months, the patient's body mass index (BMI) improved from 28 to 24, and the male partner's semen analysis showed results within normal limits. The patient's thyroid-stimulating hormone (TSH) levels also returned to the normal range. Further in-vitro fertilization (IVF) treatment, including a successful embryo transfer, resulted in a positive clinical pregnancy test. This research underscores the effectiveness of alternative therapies like yoga and meditation in conjunction with traditional medicine to address both the psychological and physiological components of infertility caused by hypothyroidism. The case suggests that an integrated approach like this could offer a comprehensive solution for infertile couples. However, for broader applicability, additional investigation and clinical validation are warranted.

## Linked entities

- **Chemicals:** levothyroxine (PubChem CID 5819)
- **Diseases:** hypothyroidism (MONDO:0005420)

## Full-text entities

- **Diseases:** Thyroid Dysfunction (MESH:D013959), hypothyroidism (MESH:D007037), infertility (MESH:D007246)
- **Chemicals:** levothyroxine (MESH:D013974)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC10900172/full.md

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Source: https://tomesphere.com/paper/PMC10900172