# Evaluation of intravenous amoxicillin-clavulanate use in two Canadian hospitals

## TL;DR

This paper evaluates the use of intravenous amoxicillin-clavulanate in Canadian hospitals as an alternative to other antibiotics.

## Contribution

The study introduces and evaluates the clinical use of a newly available antibiotic in Canada.

## Key findings

- Most patients were successfully switched from other antibiotics to amoxicillin-clavulanate.
- The drug was effective for treating respiratory and skin infections.
- It offers a good alternative due to increasing resistance to other antibiotics.

## Abstract

We describe our experience with intravenous amoxicillin-clavulanate, which is new to the Canadian market. The majority of patients were successfully de-escalated from piperacillin-tazobactam or a carbapenem for respiratory infections or skin and soft tissue infections. Intravenous amoxicillin-clavulanate provides a good alternative in an era of rising Pseudomonas aeruginosa resistance.