The Association Between Urbanization and Electrocardiogram Abnormalities in China: a Nationwide Longitudinal Study
Jiarun Mi, Xueyan Han, Man Cao, Zhaoyang Pan, Jian Guo, Dengmin Huang, Wei Sun, Yuanli Liu, Tao Xue, Tianjia Guan

TL;DR
This study finds that urbanization in China is linked to lower risks of ECG abnormalities, suggesting potential cardiovascular benefits.
Contribution
The study introduces a novel nationwide longitudinal analysis linking urbanization metrics to subclinical cardiovascular risks.
Findings
Higher urbanization levels correlate with reduced odds of ECG abnormalities.
A U-shaped relationship exists between urbanization and ECG abnormalities.
Urbanization currently benefits cardiovascular health in Chinese adults.
Abstract
The health effects of urbanization are controversial. The association between urbanization and reversible subclinical risks of cardiovascular diseases (e.g., electrocardiogram (ECG) abnormalities) has rarely been studied. This study aimed to assess the association between urbanization and ECG abnormalities in China based on the China National Stroke Screening Survey (CNSSS). We used changes in the satellite-measured impervious surfaces rate and nighttime light data to assess the level of urbanization. Every interquartile increment in the impervious surfaces rate or nighttime light was related to a decreased risk of ECG abnormalities, with odds ratios of 0.894 (95% CI, 0.869–0.920) or 0.809 (95% CI, 0.772–0.847), respectively. And we observed a U-shaped nonlinear exposure–response relationship curve between the impervious surfaces rate and ECG abnormalities. In conclusion, the current…
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Taxonomy
TopicsCardiovascular Health and Risk Factors · Global Public Health Policies and Epidemiology · Heart Rate Variability and Autonomic Control
