# Endoscopic endonasal transsphenoidal surgery for unusual sellar lesions: eight cases and review of the literature

**Authors:** Jiandong Wu, Peng Deng, Jinhong Qian, Yanli Lu, Zhiliang Ding, Xiaolong Hu, Yuhui Gong, Xiaoyu Tang, Mian Ma

PMC · DOI: 10.3389/fneur.2024.1309691 · 2024-02-13

## TL;DR

This study examines eight unusual sellar region cases treated with endoscopic surgery, highlighting successful outcomes and diagnostic insights.

## Contribution

The paper presents a case series of rare sellar lesions and their successful treatment using EETS.

## Key findings

- Eight unusual sellar lesions were successfully treated with endoscopic endonasal transsphenoidal surgery.
- Postoperative recovery was uneventful without diabetes insipidus or visual impairment.
- Specific imaging and clinical features can aid in preoperative diagnosis of these lesions.

## Abstract

Preoperative imaging for some unusual lesions in the sellar region can pose challenges in establishing a definitive diagnosis, impacting treatment strategies.

This study is a retrospective analysis of eight cases involving unusual sellar region lesions, all treated with endoscopic endonasal transsphenoidal surgery (EETS). We present the clinical, endocrine, and radiological characteristics, along with the outcomes of these cases.

Among the eight cases, the lesions were identified as follows: Solitary fibrous tumor (SFT) in one case, Lymphocytic hypophysitis (LYH) in one case, Cavernous sinus hemangiomas (CSH) in one case, Ossifying fibroma (OF) in two cases; Sphenoid sinus mucocele (SSM) in one case, Pituitary abscess (PA) in two cases. All patients underwent successful EETS, and their diagnoses were confirmed through pathological examination. Postoperatively, all patients had uneventful recoveries without occurrences of diabetes insipidus or visual impairment.

Our study retrospectively analyzed eight unusual lesions of the sellar region. Some lesions exhibit specific imaging characteristics and clinical details that can aid in preoperative diagnosis and inform treatment strategies for these unusual sellar diseases.

## Linked entities

- **Diseases:** diabetes insipidus (MONDO:0004782)

## Full-text entities

- **Diseases:** PA (MESH:D000038), OF (MESH:D018214), visual impairment (MESH:D014786), CSH (MESH:D006392), SFT (MESH:D054364), SSM (MESH:D009078), diabetes insipidus (MESH:D003919), sellar lesions (MESH:D009059), LYH (MESH:D000069281), sellar diseases (MESH:D004194)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10896968/full.md

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Source: https://tomesphere.com/paper/PMC10896968