# Age and Comorbidity Profiles as Predictors of Mechanical Ventilation Duration in COVID-19 ICU Patients: A Retrospective Study in Saudi Arabia

**Authors:** Taqi Alhaid, Jafar A Alkathem, Anisah M Humedi, Abrar A Alatawi, Rahaf A Alradady, Mazen Mohamed, Ayman M Kharaba

PMC · DOI: 10.7759/cureus.52976 · 2024-01-26

## TL;DR

This study shows that older age and conditions like diabetes and hypertension are linked to longer mechanical ventilation in ICU patients with COVID-19.

## Contribution

The study provides empirical evidence from Saudi Arabia on how age and comorbidities affect ventilation duration in critical COVID-19 patients.

## Key findings

- Older ICU patients with COVID-19 required longer mechanical ventilation.
- Comorbidities like diabetes and hypertension were associated with prolonged ventilation.
- Findings support the need for personalized ICU treatment strategies for high-risk patients.

## Abstract

Background

The COVID-19 pandemic has highlighted the critical importance of understanding factors that impact outcomes for intensive care unit patients, especially those necessitating mechanical ventilation. This study aims to examine the influence of age and comorbidities on the duration of mechanical ventilation among COVID-19 patients in ICU settings, building on existing research that indicates the significant effects of these factors on patient outcomes.

Methods

A retrospective observational study was conducted involving COVID-19 patients in ICU who required mechanical ventilation. Selection criteria included ICU admission and the necessity for mechanical ventilation. Data collection focused on patient demographics, specifically age and comorbidities such as diabetes and hypertension, alongside the total duration of mechanical ventilation. The analysis utilized descriptive statistics, comparative methods, and regression modeling.

Results

The analysis revealed that older patients and those with certain comorbidities, notably diabetes and hypertension, typically experienced prolonged periods of mechanical ventilation. These findings are consistent with existing literature, underscoring the critical role of age and comorbidity in the management of COVID-19, in ICU patients.

Conclusion

This study sheds light on the significant factors influencing the duration of mechanical ventilation in COVID-19 ICU patients. The results emphasize the need for personalized treatment approaches in the ICU, particularly for older patients and those with specific comorbidities. These insights have substantial implications for clinical practice and public health, indicating the necessity for adaptable ventilation strategies and informed resource allocation. Furthermore, the findings pave the way for future research aimed at optimizing treatment protocols for diverse patient demographics in critical care settings.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** diabetes (MESH:D003920), hypertension (MESH:D006973), COVID-19 (MESH:D000086382), Comorbidity (MESH:D004194)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC10893997