# Lichen Planopilaris As Part of Multiple Autoimmune Syndrome: A Case Report of New Association

**Authors:** Heba R Hamad, Shoroq Alamin, Moteb A Alotaibi

PMC · DOI: 10.7759/cureus.52892 · Cureus · 2024-01-24

## TL;DR

This case report describes a rare instance of lichen planopilaris linked to multiple autoimmune diseases in a single patient.

## Contribution

The paper presents the first known case of lichen planopilaris associated with multiple autoimmune syndrome.

## Key findings

- A patient with hypothyroidism and Crohn’s disease was diagnosed with lichen planopilaris.
- This case highlights the potential for lichen planopilaris to be part of multiple autoimmune syndrome.
- The findings suggest a possible link between lichen planopilaris and other autoimmune conditions.

## Abstract

Lichen planopilaris (LPP) is an uncommon inflammatory scalp condition. Its typical clinical presentation includes scaly, erythematous plaques resulting in irreversible alopecia. In this study, we report a female in her late 30s with hypothyroidism and Crohn’s disease. She presented with gradual, localized hair loss that had been ongoing for the past four months. A thorough physical examination, and complemented by dermoscopic evaluation, confirmed the diagnosis of LPP. Individuals who have an autoimmune disease (AID) have a heightened propensity to develop additional AID. The coexistence of three or more AIDs falls under the definition of multiple autoimmune syndrome (MAS). This is the first case, to the best of our knowledge, of LPP being associated with MAS.

## Linked entities

- **Diseases:** hypothyroidism (MONDO:0005420), Crohn’s disease (MONDO:0005011), lichen planopilaris (MONDO:0018879)

## Full-text entities

- **Diseases:** alopecia (MESH:D000505), Crohn's disease (MESH:D003424), AID (MESH:D001327), inflammatory scalp condition (MESH:C538225), hypothyroidism (MESH:D007037), LPP (MESH:D008010)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10891439/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC10891439/full.md

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Source: https://tomesphere.com/paper/PMC10891439