# Scleroderma Associated With Organising Pneumonia and Polyarthritis: A Report of a Rare Case

**Authors:** Bingu Shiv Kiran Reddy, Babaji Ghewade, Ulhas Jadhav, Pankaj Wagh

PMC · DOI: 10.7759/cureus.52886 · Cureus · 2024-01-24

## TL;DR

This paper reports a rare case where scleroderma and inflammatory polyarthritis were linked to organizing pneumonia as an initial symptom.

## Contribution

The novelty lies in presenting a rare clinical case where organizing pneumonia was the initial manifestation of scleroderma and polyarthritis.

## Key findings

- Organizing pneumonia can be the initial clinical sign of scleroderma and polyarthritis.
- The case highlights the complex interplay between autoimmune conditions and lung disease.
- Such presentations are rare and their clinical features remain poorly understood.

## Abstract

Cryptogenic organising pneumonia (COP) is a form of idiopathic diffuse interstitial lung disease (ILD) that develops in response to a variety of unknown irritants. An essential component of the development of organising pneumonia (OP) is damage to type II pneumocytes and the alveolar basement membrane. An autoimmune illness called systemic sclerosis (SSc) has a significant death rate from cardiopulmonary involvement such as pulmonary hypertension and ILD. Arthritis is an autoimmune disorder, in which the patients experience extra-articular symptoms such as ILD during the course of their disease, and COP frequently coexists with these conditions. It is exceedingly uncommon for OP to occur as the initial sign of arthritis, and its clinical characteristics are still unclear. Scleroderma and inflammatory polyarthritis related to COP are presented in this report.

## Linked entities

- **Diseases:** systemic sclerosis (MONDO:0005100), pulmonary hypertension (MONDO:0005149), interstitial lung disease (MONDO:0015925), arthritis (MONDO:0005578), scleroderma (MONDO:0005100)

## Full-text entities

- **Diseases:** SSc (MESH:D012595), autoimmune disorder (MESH:D001327), Arthritis (MESH:D001168), COP (MESH:D018549), ILD (MESH:D017563), OP (MESH:D011014), cardiopulmonary involvement (MESH:D006323), pulmonary hypertension (MESH:D006976), death (MESH:D003643)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10891365/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC10891365/full.md

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Source: https://tomesphere.com/paper/PMC10891365