# Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases

**Authors:** Mohamed Kamel, Sami Aleya, Majed Alsubih, Lotfi Aleya

PMC · DOI: 10.3390/jpm14020217 · 2024-02-18

## TL;DR

This review explores how the human microbiome can be harnessed to develop new strategies for fighting infectious diseases.

## Contribution

The paper highlights the microbiome's role as a mediator in host-pathogen interactions and proposes it as a target for innovative treatments.

## Key findings

- The microbiome plays a crucial role in host-pathogen interactions.
- Harnessing the microbiome offers potential for innovative treatment strategies.
- Recent advances suggest targeting the microbiome could revolutionize disease management.

## Abstract

Infectious diseases have long posed a significant threat to global health and require constant innovation in treatment approaches. However, recent groundbreaking research has shed light on a previously overlooked player in the pathogenesis of disease—the human microbiome. This review article addresses the intricate relationship between the microbiome and infectious diseases and unravels its role as a crucial mediator of host–pathogen interactions. We explore the remarkable potential of harnessing this dynamic ecosystem to develop innovative treatment strategies that could revolutionize the management of infectious diseases. By exploring the latest advances and emerging trends, this review aims to provide a new perspective on combating infectious diseases by targeting the microbiome.

## Full-text entities

- **Diseases:** Infectious Diseases (MESH:D003141)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10890469/full.md

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Source: https://tomesphere.com/paper/PMC10890469