# Experimental Lab Tests on Rabbits for the Optimization and Redesign of Low-Cost Equipment for Automated Peritoneal Dialysis

**Authors:** Sergio Rodrigo Méndez-García, Edgar Cano-Europa, José Ocotitla-Hernández, Margarita Franco-Colín, Oscar Iván Florencio-Santiago, Christopher René Torres-SanMiguel

PMC · DOI: 10.3390/bioengineering11020114 · Bioengineering · 2024-01-24

## TL;DR

This paper describes lab tests on rabbits to improve a low-cost automated peritoneal dialysis machine for future development.

## Contribution

The study identifies key improvements for an automated dialysis machine using rabbit testing and peristaltic pumps.

## Key findings

- Testing on rabbits with kidney damage revealed necessary improvements for the APD machine.
- Using peristaltic pumps instead of disposable cassettes is a promising alternative.
- The results guide future research to enhance the machine's functionality.

## Abstract

This work shows the experiences acquired by the experimental test performed to validate an automated peritoneal dialysis machine using rabbits with kidney damage to find improvements that can be made for future advances. These are listed to understand the direction of the development of the machine. The article shows the device’s background and previous tests using a testbed. The rabbit anatomy was prepared for nephrectomy surgery. The tests were practiced by checking all of the APD machine’s subsystems. The data were analyzed to develop improvements in the process. The results indicate the importance of the DPA machine as an alternative by implementing peristaltic pumps to substitute disposable cassettes. The identified improvements are the main objectives for research to continue improving the technology.

## Full-text entities

- **Diseases:** kidney damage (MESH:D007674)
- **Species:** Oryctolagus cuniculus (domestic rabbit, species) [taxon 9986]

## Full text

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## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10886354/full.md

## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC10886354/full.md

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Source: https://tomesphere.com/paper/PMC10886354