# Conservative Management With a Multimodal Approach of a 12-Week Cervical Ectopic Pregnancy With Fetal Megacystis

**Authors:** Daniela Nuti Oprescu, Ana Elena Martiniuc, Monica Mihaela Cirstoiu, Elena Theodora Giubegeanu, Oana Daniela Toader

PMC · DOI: 10.7759/cureus.52771 · Cureus · 2024-01-23

## TL;DR

A rare cervical ectopic pregnancy was successfully managed with conservative methods to preserve fertility.

## Contribution

Presents a novel conservative treatment approach for advanced cervical ectopic pregnancy.

## Key findings

- Combination of embolization, medication, and surgical techniques preserved fertility.
- Patient recovered uneventfully after treatment and was discharged within three days.
- No specific guidelines exist for managing advanced cervical pregnancies.

## Abstract

Cervical ectopic pregnancy is the rarest kind of ectopic pregnancy, and it is known as the implantation of an embryo into the cervical mucosa. It is commonly associated with complications such as hemorrhage from the cervix and can lead to severe consequences if it is not treated early. For this reason, the treatment for a cervical pregnancy often requires an abdominal hysterectomy. To avoid such radical management, several conservative methods of termination have been used. In this paper, we report a complex management of one of our ectopic cervical cases, which includes embolization of the uterine arteries, treatment with methotrexate and mifepristone, evacuation of the pregnancy followed by local hemostatic sutures and application of a balloon in the cervix. The post-operative period was uneventful. After a three-day postoperative stay, the patient was discharged. The management options employed in the presented case achieved the goal of preserving fertility for our patient. There are no specific guidelines for the treatment of cervical pregnancies in advanced gestational age.

## Linked entities

- **Chemicals:** methotrexate (PubChem CID 4112), mifepristone (PubChem CID 4196)

## Full-text entities

- **Diseases:** ectopic cervical (MESH:D002575), Cervical Ectopic Pregnancy (MESH:D011271), Fetal Megacystis (MESH:C536139), hemorrhage (MESH:D006470)
- **Chemicals:** mifepristone (MESH:D015735), methotrexate (MESH:D008727)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC10884779/full.md

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Source: https://tomesphere.com/paper/PMC10884779