Retraction: Tidal Stretches Differently Regulate the Contractile and Cytoskeletal Elements in Intact Airways

Abstract

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After publication of this article [1], concerns were raised about similarities between some GAPDH loading control bands (hereafter, LCs) in western blots in Figs 2, 3, and 7.

Specifically,

During editorial follow up, the corresponding author provided the available underlying blot images for these published figures, as well as replicate blot data. Additional methodological information regarding the western blot experiments was also provided to clarify that some loading control panels (left- and right-hand panels of Fig 7A; Fig 2D and Fig 3D) were correctly duplicated because the same membrane was re-probed for different proteins of interest. However, some original blot data needed to address the concerns are now unavailable and so questions about the reliability of the published loading control blots could not be fully resolved. The corresponding author requested retraction of this article.

In light of the unresolved concerns about the reliability of loading control image data in the published figures, the PLOS ONE Editors retract this article.

EBS and BS agreed with retraction and stand by the article’s findings. ASLP, BCH, and KRL either did not respond directly or could not be reached.