# Exploring synergies between B- and T-cell vaccine approaches to optimize immune responses against HIV—workshop report

## TL;DR

This workshop explored combining B-cell and T-cell vaccine strategies to improve immune responses against HIV.

## Contribution

The paper summarizes a workshop focused on synergies between cellular and humoral HIV vaccine approaches.

## Key findings

- Leading vaccine candidates were reviewed for their potential to induce immune responses.
- Strategies for combining B-cell and T-cell approaches were discussed to optimize immunity.
- Knowledge gaps and future research priorities were identified to accelerate HIV vaccine development.

## Abstract

The US National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institute of Health (NIH), convened a virtual workshop on August 8-9th, 2023 to explore potential synergies between HIV vaccine approaches that are designed to induce cellular or humoral immune responses. The goal of this workshop was to review data on leading vaccine candidates and to discuss the best strategies for combining these approaches to optimize immunity against HIV. Here, we summarize the findings reviewed at the workshop and discuss the knowledge gaps and priorities for future studies that will help accelerate the development of a preventive HIV vaccine.