# Audiovisualization of real-time neuroimaging data

**Authors:** David N. Thibodeaux, Mohammed A. Shaik, Sharon H. Kim, Venkatakaushik Voleti, Hanzhi T. Zhao, Sam E. Benezra, Chinwendu J. Nwokeabia, Elizabeth M. C. Hillman

PMC · DOI: 10.1371/journal.pone.0297435 · PLOS ONE · 2024-02-21

## TL;DR

This paper introduces a method to convert real-time brain imaging data into audiovisualizations, helping researchers better understand complex brain activity patterns.

## Contribution

The novel approach uses audiovisual representations to encode multiple variables as musical instruments for intuitive data exploration.

## Key findings

- Audiovisualizations allow for the simultaneous tracking of multiple dynamic parameters in neuroimaging data.
- This method reveals spatiotemporal patterns and rhythms that are hard to detect with traditional methods.
- The approach offers a compelling and intuitive way to visualize complex brain activity for broader applications.

## Abstract

Advancements in brain imaging techniques have significantly expanded the size and complexity of real-time neuroimaging and behavioral data. However, identifying patterns, trends and synchronies within these datasets presents a significant computational challenge. Here, we demonstrate an approach that can translate time-varying neuroimaging data into unique audiovisualizations consisting of audible representations of dynamic data merged with simplified, color-coded movies of spatial components and behavioral recordings. Multiple variables can be encoded as different musical instruments, letting the observer differentiate and track multiple dynamic parameters in parallel. This representation enables intuitive assimilation of these datasets for behavioral correlates and spatiotemporal features such as patterns, rhythms and motifs that could be difficult to detect through conventional data interrogation methods. These audiovisual representations provide a novel perception of the organization and patterns of real-time activity in the brain, and offer an intuitive and compelling method for complex data visualization for a wider range of applications.

## Full-text entities

- **Genes:** Thy1 (thymus cell antigen 1, theta) [NCBI Gene 21838] {aka CD90, T25, Thy-1, Thy-1.2, Thy1.1, Thy1.2}
- **Diseases:** analgesia (MESH:D000699)
- **Chemicals:** GCaMP (-), calcium (MESH:D002118), Ketamine (MESH:D007649), cyanoacrylate (MESH:D003487), Xylazine (MESH:D014991), isoflurane (MESH:D007530)
- **Species:** Homo sapiens (human, species) [taxon 9606], Mus musculus (house mouse, species) [taxon 10090]
- **Cell lines:** S2 — Drosophila melanogaster (Fruit fly), Spontaneously immortalized cell line (CVCL_Z232), C57BL/6J — Mus musculus (Mouse), Transformed cell line (CVCL_C0MW)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10881001/full.md

## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC10881001/full.md

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Source: https://tomesphere.com/paper/PMC10881001