# Ocular surface squamous neoplasia masquerading as pseudoepitheliomatous hyperplasia in chronic vernal keratoconjunctivitis

## TL;DR

A rare case of a rare eye tumor was mistaken for a benign condition in a patient with long-term eye inflammation.

## Contribution

Highlights the diagnostic challenge of distinguishing OSSN from pseudoepitheliomatous hyperplasia in chronic VKC.

## Key findings

- A 24-year-old man with chronic VKC was found to have OSSN with mild to moderate dysplasia.
- The case emphasizes the need for detailed cytological and histopathological examination for accurate diagnosis.
- Treatment included excision biopsy, cryotherapy, and amniotic membrane transplantation.

## Abstract

We report a rare case of ocular surface squamous neoplasia (OSSN) masquerading as pseudoepitheliomatous hyperplasia in chronic vernal keratoconjunctivitis (VKC). A 24-year-old man presented with a history of bilateral VKC since childhood with a superior limbal mass in the right eye. There was a history of use of intermittent corticosteroids in the past. He underwent impression cytology followed by excision biopsy with wide margins (no touch technique), cryotherapy and amniotic membrane transplantation. Histopathological analysis confirmed the diagnosis of OSSN with mild to moderate dysplasia. This case highlights the importance of strong clinical suspicion and detailed cytological and histopathological examination for early detection and management of OSSN.