# Atypical Papillary Dysplasia of the Bladder Neck

**Authors:** Nikit Venishetty, Meesha Trivedi, Jeffrey Annabi, Angelica Padilla, Hani Annabi

PMC · DOI: 10.7759/cureus.52726 · Cureus · 2024-01-22

## TL;DR

This case study explores a rare bladder cancer form in a prostate cancer patient, emphasizing the need for more research on atypical dysplastic lesions.

## Contribution

The study presents a unique case of atypical papillary dysplasia in a bladder tumor, highlighting its potential to progress to cancer.

## Key findings

- A 65-year-old man with prostate cancer showed bladder atypical papillary dysplasia.
- The lesion appeared raspberry-colored and showed significant urothelial proliferation.
- The study stresses the importance of identifying such lesions for cancer prevention.

## Abstract

As the fourth most frequent disease in men, bladder cancer has a significant financial impact on healthcare. Because atypical dysplasia and papillary forms in bladder cancer are uncommon, there is a dearth of information on them. This study attempts to fill that gap. In the case study that is being presented, a 65-year-old man with a history of prostate cancer was admitted due to unusual urine cytology results that showed bladder papillary atypia. A distinct lesion on the bladder's dome that resembled a raspberry color was discovered by cystoscopy and transurethral resection of the bladder tumor (TURBT), which led to numerous biopsies and resections. Pathology demonstrated a significant urothelial proliferation. The study highlights the variety of morphologies found in atypical dysplastic lesions and the possibility that these lesions could develop into cancer. The significance of identifying atypical dysplastic lesions is emphasized in the study's conclusion, notably in patients with a history of prostate cancer, and highlights the need for further investigation in this domain.

## Linked entities

- **Diseases:** bladder cancer (MONDO:0004986), prostate cancer (MONDO:0005159)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** bladder cancer (MESH:D001749), cancer (MESH:D009369), dysplasia (MESH:D015792), dysplastic lesions (MESH:D004416), Papillary Dysplasia of the Bladder Neck (MESH:D001748), prostate cancer (MESH:D011471), proliferation (MESH:C565054)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10879739/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC10879739/full.md

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Source: https://tomesphere.com/paper/PMC10879739