# Validation of phenomenon and cross-sectional investigation of predictors for a post-COVID-19 surge of osteoporosis outpatients in China

**Authors:** Lei Sun, Yuehua Zhang, Yao Chen, Li Chen, Mei Lei

PMC · DOI: 10.1038/s41598-024-54858-4 · Scientific Reports · 2024-02-20

## TL;DR

After China's COVID-19 lockdown ended, more people sought osteoporosis care, likely due to factors like pain and anxiety.

## Contribution

Identified four predictors of increased osteoporosis outpatient visits following pandemic lockdowns in China.

## Key findings

- Female gender, pain, worsening symptoms, and heightened anxiety during lockdown predicted post-lockdown care-seeking.
- Physical activity levels during lockdown did not significantly predict outpatient visits.
- The surge in visits suggests a backlog of unmet healthcare needs for osteoporosis during the pandemic.

## Abstract

An unexpected surge of osteoporosis outpatients occurred after COVID-19 lockdown was lifted in China. To confirm the observation and identify possible reasons driving patients care seeking behaviors post-pandemic, we compared the outpatient volumes at the osteoporosis clinic in January through May, 2019–2022 and surveyed seven osteoporosis specialists across China to validate the phenomenon before devising an online questionnaire to collect patients’ characters and physical activity levels. Univariate and binary logistic regression analyses were calculated to identify predictors of post-lockdown care-seeking. We received 480 valid responses, including 397 (82.7%) patients having visited the clinic after lockdown and 83 (17.3%) having not. Four significant predictors were identified, including being female, experiencing pain, aggravating symptoms, and heightened anxiety during lockdown (P < 0.05). Both groups experienced lower physical activity levels during lockdown, which however was not a significant predictor (P = 0.317). The surge in osteoporosis outpatient visits after COVID-19 lockdown suggests vast latent demand for osteoporosis care accumulated during the pandemic. Four significant factors predict post-lockdown outpatient care-seeking, including being female, experiencing pain and aggravating symptoms, and heightened anxiety levels. Though physical activity levels decreased during lockdown, it failed to predict care-seeking. This demonstrates resilience of osteoporosis patients to resume regular care despite disruption and stress the substantial backlog of unmet healthcare needs.

## Linked entities

- **Diseases:** osteoporosis (MONDO:0005298), COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** anxiety (MESH:D001007), osteoporosis (MESH:D010024), COVID-19 (MESH:D000086382), pain (MESH:D010146), post-COVID-19 (MESH:D000094024)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## Figures

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## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC10879099/full.md

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Source: https://tomesphere.com/paper/PMC10879099