# Massive extrapancreatic solid pseudopapillary neoplasm misdiagnosed as hepatic tumor: a case report and literature review

**Authors:** Jixu Guo, Qingjuan Zhao, Liting Qin, Shengjie Xie, Shiliu Lu, Baibei Li, Meilin He, Linhong Xie, Shuiping Yu

PMC · DOI: 10.3389/fonc.2024.1342400 · Frontiers in Oncology · 2024-02-06

## TL;DR

A rare case of a tumor originally mistaken for liver cancer was correctly identified as a pancreatic-related neoplasm after surgery.

## Contribution

This case report highlights the diagnostic challenges and management of extrapancreatic solid pseudopapillary neoplasms.

## Key findings

- The tumor was misdiagnosed as hepatocellular carcinoma but confirmed as extrapancreatic SPN post-surgery.
- Surgical resection was effective and the patient remained asymptomatic after 15 months.
- Accurate diagnosis is crucial for proper treatment of liver masses.

## Abstract

Solid pseudopapillary neoplasms (SPNs) of the pancreas are uncommon, low-malignancy neoplasms. Moreover, the occurrence of extrapancreatic SPNs is rarely encountered.

A 45-year-old female presented with a right upper abdominal mass and abdominal pain for 3 and 1 months as chief complaints, respectively. Initially, the patient was misdiagnosed with hepatocellular carcinoma based on her symptoms and results of physical and imaging examinations. Following multidisciplinary discussion and ruling out surgical contraindications, a decision was taken to proceed with surgical intervention. Interestingly, the tumor was found to originate from the retroperitoneum and had invaded the right half of the liver and the right wall of the inferior vena cava. The operation was uneventful, and the pathological findings confirmed the tumor as an extrapancreatic SPN. The patient remained asymptomatic after 15 months of follow-up.

Surgical treatment remains the preferred option for extrapancreatic SPN. The preoperative misdiagnosis also highlights the importance of accurate diagnosis and the development of appropriate treatment strategies for liver masses.

## Linked entities

- **Diseases:** hepatocellular carcinoma (MONDO:0007256)

## Full-text entities

- **Diseases:** abdominal mass (MESH:D000007), of the pancreas (MESH:D010190), abdominal pain (MESH:D015746), hepatocellular carcinoma (MESH:D006528), SPNs (MESH:D009369), liver masses (MESH:D008107)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC10877141/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10877141/full.md

## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC10877141/full.md

---
Source: https://tomesphere.com/paper/PMC10877141