Slimmer’s Palsy Following Weight Loss Associated With Metastatic Breast Cancer: A Case Report

TL;DR

A woman with metastatic breast cancer developed Slimmer’s Palsy after rapid weight loss, highlighting a rare neurological complication linked to cancer.

Contribution

This case report adds to the understanding of CPN's association with malignancy and rapid weight loss.

Findings

CPN occurred in a patient with metastatic breast cancer following significant weight loss.

The condition presented as left foot drop and paresthesias.

The case highlights the need for neurological evaluation in cancer patients with unexplained weight loss.

Abstract

Common peroneal neuropathy (CPN), also known as Slimmer’s Palsy, is an isolated peripheral neuropathy typically associated with rapid weight loss resulting in loss of adipose tissue and subsequent nerve compression at the fibular head and is up to three times more common in individuals with malignancy. In this case report, we describe the diagnosis of CPN in a 54-year-old female with a 2.5-month history of atraumatic left foot drop and left ankle paresthesias, preceded by a 35-40 pound weight loss over the prior 3.5 month period in the setting of metastatic breast cancer.

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