# Retroperitoneal paraduodenal unicentric Castleman disease: case report and review of the literature

## TL;DR

A rare case of Castleman disease was found near the duodenum in a 57-year-old man, highlighting the importance of considering this diagnosis in similar cases.

## Contribution

This case report adds to the limited literature on paraduodenal unicentric Castleman disease, emphasizing its rarity and diagnostic significance.

## Key findings

- The patient had a retroperitoneal mass diagnosed as hyaline-vascular Castleman disease.
- Only two similar cases of paraduodenal unicentric Castleman disease have been previously reported.
- Laparoscopic removal was successful without complications.

## Abstract

Castleman disease is a rare and benign disorder, characterized by enlarged lymph nodes and angiofollicular lymphoid hyperplasia. We report a case of a 57-year-old male, who was admitted to our surgical department because of a retroperitoneal nodular mass measuring about 4 cm in maximum diameter, incidentally discovered on a radiologic exam performed for the onset of vague abdominal pain with posterior irradiation. The patient was subdue to laparoscopic removal of the mass and no intra- and post-operative complications were recorded. Histologic diagnosis of hyaline-vascular variant of the Castleman disease was confirmed. Only two cases have been found in the literature reporting the paraduodenal unicentric Castleman disease localization like our case. Although rare, the Castleman disease must be considered in the differential diagnosis among all the lymph nodes diseases, for avoiding improper therapies.