Adult-Onset Multifocal Cutaneous Myofibromas: A Case Report of a Rare Entity

TL;DR

This paper reports a rare case of a 57-year-old woman with two soft tissue lesions on her leg diagnosed as adult-onset multifocal cutaneous myofibromas.

Contribution

This is the first reported case of adult-onset multifocal cutaneous myofibromas in the literature.

Findings

The patient had two minimally symptomatic soft tissue lesions on her right leg.

Pathologic findings confirmed both lesions were consistent with cutaneous myofibromas.

Abstract

Myofibromas are observed in both infantile and adult presentations, with key differences in the number and severity of lesions between these two groups. Infantile presentations encompass both indolent, isolated cutaneous lesions, as well as aggressive, multicentric presentations with visceral involvement. Adult myofibromas appear to be characterized by a single isolated cutaneous lesion, generally asymptomatic and following a benign clinical course. The occurrence of adult multifocal myofibromas has not yet been described in the literature. Here, we report a case of a 57-year-old female who presented with two minimally symptomatic soft tissue lesions on her right leg, with the pathologic findings of each lesion consistent with a cutaneous myofibroma. This case report describes a rare presentation of adult-onset multifocal cutaneous myofibromas.

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