# Rivaroxaban Failure Presenting With Renal Infarction in a Patient With Persistent Atrial Fibrillation: A Case Report

**Authors:** Shudipan Chakraborty, Fnu Salman, Moaaz Baghal, Ayesha Tahir, Abdul Baqi, Hemindermeet Singh, Mohammed Taleb

PMC · DOI: 10.7759/cureus.52332 · Cureus · 2024-01-15

## TL;DR

A patient with atrial fibrillation on rivaroxaban experienced a rare case of anticoagulant failure leading to a renal infarction.

## Contribution

This case report highlights a rare instance of rivaroxaban failure resulting in left renal infarction.

## Key findings

- Rivaroxaban failure led to left renal infarction in a patient with atrial fibrillation.
- The patient had dense spontaneous echocardiographic contrast in the left atrium.
- DOAC failure is rare but can result in severe complications like renal infarction.

## Abstract

Direct oral anticoagulants (DOAC) are the preferred choice of anticoagulation for patients with atrial fibrillation. DOACs are always preferred over vitamin K antagonists due to their better safety profile in terms of life-threatening bleeding and decreased need for INR (international normalised ratio) monitoring. Although the most commonly used anticoagulation, failure to DOAC has been reported. Here we present a rare case of rivaroxaban failure presenting with left renal infarction in a patient who had dense spontaneous echocardiographic contrast in the left atrium visualised by transthoracic echocardiography.

## Linked entities

- **Chemicals:** rivaroxaban (PubChem CID 6433119)
- **Diseases:** atrial fibrillation (MONDO:0004981)

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), Atrial Fibrillation (MESH:D001281), Renal Infarction (MESH:D007238)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC10866738/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10866738/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC10866738/full.md

---
Source: https://tomesphere.com/paper/PMC10866738